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Article

The role of epithelial-to-mesenchymal transition in renal fibrosis.

Journal of molecular medicine (Berlin, Germany) - 1 Mar 2004

Zeisberg Michael, Kalluri Raghu

Abstract excerpt

Epithelial-to-mesenchymal transition (EMT) involving injured epithelial cells plays an important role in the progression of fibrosis in the kidney. Tubular epithelial cells can acquire a mesenchymal phenotype, and enhanced migratory capacity enabling them to transit from the renal tubular microenvironment into the interstitial space and escape potential apoptotic cell death. EMT is a major contributor to the...

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Identifiers

PMID: 14752606
DOI: 10.1007/s00109-003-0517-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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