Article
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for genotyping of human platelet-specific antigens.
Transfusion - 1 Feb 2009
Garritsen Henk S P, Fan Alex Xiu-Cheng, Bosse Nicole, Hannig Horst, Kelsch Reinhard, Kroll Hartmut, Holzgreve Wolfgang, Zhong Xiao Yan
Abstract excerpt
BACKGROUND: Genotyping of single-nucleotide polymorphisms (SNPs) using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is an emerging technique, where finally tools for end users have become available to design primers and analyze SNPs of their own interest. This study investigated the potential of this technique in platelet (PLT) genotyping and developed a validated...
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