Article
Fully genotyping and screening of clinically important blood-group antigens by MALDI TOF mass spectrometry.
Electrophoresis - 1 Mar 2024
Yang Qixiu, Li Aijing, Wang Chen, Yang Jiaxuan, Li Minghao, Zhu Huijun, Lu Daru, Zhu Ziyan, Ye Luyi
Abstract excerpt
Several molecular biology methods are available for high-throughput blood typing. In this study, we aimed to build a high-throughput blood-group genetic screening system for high-frequency blood-group antigen-negative rare-blood groups in donors and patients. The amplification primers for all blood-type gene fragments involving the selected alleles were designed for detection. Single-base extend primers were also...
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