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Development of mass spectrometry-based genotyping method for simultaneous detection of 35 HPA systems, 5 HNA systems and the CD36 antigen.

Transfusion - 1 May 2026

Zhu Huijun, Li Ruishu, Fu Min, Yang Qixiu, Ma Qinqin, Lu Ping, Zhu Ziyan, Ye Luyi

Abstract excerpt

BACKGROUND: Surface antigens on platelets and neutrophils-including human platelet antigens (HPA), human neutrophil antigens (HNA), and CD36-are critical determinants of compatibility in platelet transfusion. To address the need for high-throughput genotyping, this study developed a method for simultaneous detection of 35 HPA systems, 5 HNA systems, and CD36 polymorphisms based on matrix-assisted laser...

Topics

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Antigens, Human Platelet
CD36 Antigens
Genotype
Genotyping Techniques
Isoantigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

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Identifiers

PMID: 41821186
DOI: 10.1111/trf.70167

Genes

CD36

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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