Article
Use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for multiplex genotyping.
Advances in clinical chemistry - 1 Jan 2011
Meyer Klaus, Ueland Per Magne
Abstract excerpt
After completion of the human genome project, the focus of geneticists has shifted to elucidation of gene function and genetic diversity to understand the mechanisms of complex diseases or variation of patient response in drug treatment. In the past decade, many different genotyping techniques have been described for the detection of single-nucleotide polymorphisms (SNPs) and other common polymorphic variants....
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