Rapid and/or high-throughput genotyping for human red blood cell, platelet and leukocyte antigens, and forensic applications.

Abstract excerpt

BACKGROUND: Traditionally, transfusion medicine, platelet and human leukocyte antigen (HLA) typing, and forensic medicine relied on serologic studies. METHODS: In recent years, molecular testing on nucleic acids has been increasingly applied to these areas. Although conventional molecular diagnostic methods such as PCR-sequence-specific priming, PCR-restriction fragment-length polymorphism, PCR-single-strand...

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