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Article

Next Generation Sequencing of Human Platelet Antigens for Routine Clinical Investigations and Donor Screening.

Transfusion medicine reviews - 1 Apr 2022

Guglielmino J, Jackson D E

Abstract excerpt

Human platelet antigen (HPA) genotyping is performed in a number of clinical scenarios, including characterization of immune-mediated thrombocytopenia and provision of HPA-matched platelets. Current gold-standard methods for HPA genotyping utilize single nucleotide variant (SNV) based approaches. This review aims to ascertain if next generation sequencing (NGS) has reasonable grounds to replace SNV-based...

Topics

Antigens, Human Platelet
Donor Selection
Genotype
High-Throughput Nucleotide Sequencing
Humans

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 35135721
DOI: 10.1016/j.tmrv.2022.01.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-35135721-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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