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Article

Conditional random pattern algorithm for LOH inference and segmentation.

Bioinformatics (Oxford, England) - 1 Jan 2009

Wu Ling-Yun, Zhou Xiaobo, Li Fuhai, Yang Xiaorong, Chang Chung-Che, Wong Stephen T C

Abstract excerpt

MOTIVATION: Loss of heterozygosity (LOH) is one of the most important mechanisms in the tumor evolution. LOH can be detected from the genotypes of the tumor samples with or without paired normal samples. In paired sample cases, LOH detection for informative single nucleotide polymorphisms (SNPs)...

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PMID: 18974074
DOI: 10.1093/bioinformatics/btn561
PMCID: PMC3159432

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18974074-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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