Article
An integrated Bayesian analysis of LOH and copy number data.
BMC bioinformatics - 15 Jun 2010
Rancoita Paola M V, Hutter Marcus, Bertoni Francesco, Kwee Ivo
Abstract excerpt
BACKGROUND: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleotide Polymorphisms (SNPs) along the genome. CN is defined as the number of DNA copies, and the normal is two, since we h...
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