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Article

N-terminal deletion affects catalytic activity of saporin toxin.

Journal of cellular biochemistry - 1 Aug 2006

Bonini Francesca, Traini Roberta, Comper Fabrizio, Fracasso Giulio, Tomazzolli Rossella, Dalla Serra Mauro, Colombatti Marco

Abstract excerpt

Single-chain ribosome inactivating proteins (RIPs) are cytotoxic components of macromolecular pharmaceutics for immunotherapy of cancer and other human diseases. Saporin belongs to a family of single-chain RIPs sharing sequence and structure homology. In a preliminary attempt to define an active...

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Identifiers

PMID: 16775836
DOI: 10.1002/jcb.20845

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16775836-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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