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Article

Analysis by systematic deletion of amino acids of the action of the ribotoxin restrictocin.

Biochimica et biophysica acta - 31 Jan 2002

Glück Anton, Wool Ira G

Abstract excerpt

A series of contiguous deletions were made in a cDNA encoding the ribonuclease restrictocin with the purpose of identifying the amino acids that are essential for the cleavage of the phosphodiester bond on the 3' side of G4325 in the alpha-sarcin/ricin domain of mammalian (rat) 28S rRNA. In all 93 of 149 amino acids, 62% of the residues in restrictocin, were not essential for the action of the toxin. Of the five...

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Identifiers

PMID: 11825614
DOI: 10.1016/s0167-4838(01)00290-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Analysis by systematic deletion of amino acids of the action of the ribotoxin restrictocin.PMID 11825614Read ↗

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Role of cis prolines 112 and 126 in the functional activity of ribonucleolytic toxin restrictocin.Semantic proximity Read ↗

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