Article
Positional cloning by fast-track SNP-mapping in Drosophila melanogaster.
Nature protocols - 1 Jan 2008
Schnorrer Frank, Ahlford Annika, Chen Doris, Milani Lili, Syvänen Ann-Christine
Abstract excerpt
Positional cloning of chemically induced mutations is the rate-limiting step in forward genetic screens in Drosophila. Single-nucleotide polymorphisms (SNPs) are useful markers to locate a mutated region in the genome. Here, we provide a protocol for high-throughput, high-resolution SNP mapping t...
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