Article
Single nucleotide polymorphism markers for genetic mapping in Drosophila melanogaster.
Genome research - 1 Jun 2001
Hoskins R A, Phan A C, Naeemuddin M, Mapa F A, Ruddy D A, Ryan J J, Young L M, Wells T, Kopczynski C, Ellis M C
Abstract excerpt
For nearly a century, genetic analysis in Drosophila melanogaster has been a powerful tool for analyzing gene function, yet Drosophila lacks the molecular genetic mapping tools that recently have revolutionized human, mouse, and plant genetics. Here, we describe the systematic characterization of a dense set of molecular markers in Drosophila by using a sequence tagged site-based physical map of the genome. We...
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