Article
High-resolution, high-throughput SNP mapping in Drosophila melanogaster.
Nature methods - 1 Apr 2008
Chen Doris, Ahlford Annika, Schnorrer Frank, Kalchhauser Irene, Fellner Michaela, Viràgh Erika, Kiss Istvàn, Syvänen Ann-Christine, Dickson Barry J
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are useful markers for genetic mapping experiments in model organisms. Here we report the establishment of a high-density SNP map and high-throughput genotyping assays for Drosophila melanogaster. Our map comprises 27,367 SNPs in common laboratory Drosophila stocks. These SNPs were clustered within 2,238 amplifiable markers at an average density of 1 marker every 50.3 kb, or...
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