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Article

Phosphatidylethanolamine synthesis is required for optimal virulence of Brucella abortus.

Journal of bacteriology - 1 Dec 2008

Bukata Lucas, Altabe Silvia, de Mendoza Diego, Ugalde Rodolfo A, Comerci Diego J

Abstract excerpt

The Brucella cell envelope contains the zwitterionic phospholipids phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Synthesis of PC occurs exclusively via the PC synthase pathway, implying that the pathogen depends on the choline synthesized by the host cell to form PC. Notably, PC is necessary to sustain a chronic infection process, which suggests that the membrane lipid content is relevant for...

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Identifiers

PMID: 18931122
DOI: 10.1128/JB.01069-08
PMCID: PMC2593215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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