Article
Brucella abortus synthesizes phosphatidylcholine from choline provided by the host.
Journal of bacteriology - 1 Mar 2006
Comerci Diego J, Altabe Silvia, de Mendoza Diego, Ugalde Rodolfo A
Abstract excerpt
The Brucella cell envelope is characterized by the presence of phosphatidylcholine (PC), a common phospholipid in eukaryotes that is rare in prokaryotes. Studies on the composition of Brucella abortus 2308 phospholipids revealed that the synthesis of PC depends on the presence of choline in the culture medium, suggesting that the methylation biosynthetic pathway is not functional. Phospholipid composition of pmtA...
Topics
- Amino Acid Sequence
- Animals
- Bacterial Proteins
- Brucella abortus
- Brucellosis
- Choline
- Escherichia coli
- Female
- Methyltransferases
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
