Article
Identification of genes contributing to the intracellular replication of Brucella abortus within HeLa and RAW 264.7 cells.
Veterinary microbiology - 17 Aug 2012
Kim Dong Hyeok, Lim Jeong Ju, Lee Jin Ju, Kim Dae Geun, Lee Hu Jang, Min Wongi, Kim Kwang Dong, Chang Hong Hee, Rhee Man Hee, Watarai Masahisa, Kim Suk
Abstract excerpt
Brucella abortus, the causative agent of brucellosis, can survive and replicate within host cells. Understanding bacterial virulence factors and bacteria-host cell interactions is critical for controlling brucellosis, yet very little is known about the virulence strategies and signaling pathways activated in phagocytes during infection to ensure their growth and survival. B. abortus was mutagenized by mini-Tn5Km2...
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