Article
Sphingomyelin is critical in organizing phosphoinositide dynamics during phagocytic uptake of <i>Mycobacterium tuberculosis</i>
2019-03-01
Abstract excerpt
Tuberculosis, the pathological result of infection by Mycobacterium tuberculosis ( M.tb ), represents a massive and persistent global health burden with vast overrepresentation in regions with poor access to healthcare. This pathogen survives intracellularly within lung macrophages, and has been shown to extensively reprogram the host lipid compartment to the effect of enhanced survival and immune evasion. Sphin...
Topics
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- Antibiotic Resistance in Bacteria
- Biochemical and Molecular Research
- Clostridium difficile and Clostridium perfringens research
- Drug Transport and Resistance Mechanisms
- Microbial infections and disease research
- Mycobacterium research and diagnosis
- Steroid Chemistry and Biochemistry
- Tuberculosis Research and Epidemiology
Identifiers and source
- Literature Corpus work
- 81adb4a3-8e39-5e94-9607-e569abff0969
- DOI
- 10.1101/565226
