Article
Highly selective single nucleotide polymorphism recognition by a chiral (5S) PNA beacon.
Chirality - 1 Jan 2009
Totsingan Filbert, Tedeschi Tullia, Sforza Stefano, Corradini Roberto, Marchelli Rosangela
Abstract excerpt
A chiral peptide nucleic acid (PNA) beacon containing a C-5 modified monomer based on L-lysine was synthesized. The terminal amino group of the lysine side chain was linked to a spacer for future applications on surfaces. The PNA beacon bears a carboxyfluorescein fluorophore and a dabcyl quencher...
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