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Article

Improved single nucleotide polymorphisms detection using conjugated polymer/surfactant system and peptide nucleic acid.

Biosensors & bioelectronics - 15 May 2008

Al Attar Hameed A, Norden Jean, O'Brien Stephen, Monkman Andy P

Abstract excerpt

An improved assay for the detection of single nucleotide polymorphisms (SNP) of mutant DNA using a combination of peptide nucleic acid (PNA) probes, a cationic conjugated polymer (CCP) and non-ionic surfactant is reported. A comparison between CCP/surfactant and CCP alone shows enhancement in the discrimination between mutant and wild type DNA by a factor of two. A discrimination factor of 70% and 92% was...

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Identifiers

PMID: 18296040
DOI: 10.1016/j.bios.2008.01.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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