Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Templated metal catalysis for single nucleotide specific DNA sequence detection.

Journal of the American Chemical Society - 1 Jun 2005

Boll Iris, Krämer Roland, Brunner Jens, Mokhir Andriy

Abstract excerpt

A catalytic DNA-templated reaction of hydrolysis of an ester group in an N-modified peptide nucleic acid, which is activated by a Cu2+ complex-PNA, has been discovered and optimized. Both the ester-containing PNA and the metal complex PNA bind neighboring sites on a template DNA. This brings the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Catalysis
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrolysis

Share to Nucleic Acid Conformation

Share to Peptide Nucleic Acids

Share to Sequence Analysis, DNA

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Source

Identifiers

PMID: 15913375
DOI: 10.1021/ja0503332

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15913375-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Templated metal catalysis for single nucleotide specific DNA sequence detection.PMID 15913375Read ↗

Single-nucleotide-specific PNA-peptide ligation on synthetic and PCR DNA templates.Semantic proximity Read ↗

DNA-hosted copper nanoclusters for fluorescent identification of single nucleotide polymorphisms.Semantic proximity Read ↗

Template-directed formation of luminescent lanthanide complexes: versatile tools for colorimetric identification of single nucleotide polymorphism.Semantic proximity Read ↗

High-throughput ultra-sensitive discrimination of single nucleotide polymorphism via click chemical ligation.Semantic proximity Read ↗

An efficient DNA-fueled molecular machine for the discrimination of single-base changes.Semantic proximity Read ↗

Enzyme-free amplified detection of DNA by an autonomous ligation DNAzyme machinery.Semantic proximity Read ↗

DNA nanotechnology for nucleic acid analysis: DX motif-based sensor.Semantic proximity Read ↗

Facile functionalization of peptide nucleic acids (PNAs) for antisense and single nucleotide polymorphism detection.Semantic proximity Read ↗

Expanding the DNA Damaging Potential of Artificial Metallo-Nucleases with Click ChemistrySemantic proximity Read ↗

Ligase-based multiple DNA analysis by using an electrochemical sensor array.Semantic proximity Read ↗

An Engineered Kinetic Amplification Mechanism for Single Nucleotide Variant Discrimination by DNA Hybridization Probes.Semantic proximity Read ↗

Ligation with nucleic acid sequence-based amplification.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.