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Article

SNP detection using peptide nucleic acid probes and conjugated polymers: applications in neurodegenerative disease identification.

Proceedings of the National Academy of Sciences of the United States of America - 4 Jan 2005

Gaylord Brent S, Massie Michelle R, Feinstein Stuart C, Bazan Guillermo C

Abstract excerpt

A strategy employing a combination of peptide nucleic acid (PNA) probes, an optically amplifying conjugated polymer (CP), and S1 nuclease enzyme is capable of detecting SNPs in a simple, rapid, and sensitive manner. The recognition is accomplished by sequence-specific hybridization between the un...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Share to Spectrometry, Fluorescence

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Identifiers

PMID: 15618399
DOI: 10.1073/pnas.0407578101
PMCID: PMC544065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15618399-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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