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Article

Fluorescence detection of single nucleotide polymorphisms using a universal molecular beacon.

Nucleic acids research - 1 Nov 2008

Lin Yang-Wei, Ho Hsin-Tsung, Huang Chih-Ching, Chang Huan-Tsung

Abstract excerpt

We present a simple and novel assay-employing a universal molecular beacon (MB) in the presence of Hg(2+)-for the detection of single nucleotide polymorphisms (SNPs) based on Hg(2+)-DNA complexes inducing a conformational change in the MB. The MB (T(7)-MB) contains a 19-mer loop and a stem of a p...

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PMID: 18753149
DOI: 10.1093/nar/gkn537
PMCID: PMC2577337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18753149-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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