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Article

Stereochemistry-Guided DNA Probe for Single Nucleotide Polymorphisms Analysis.

ACS applied materials & interfaces - 29 Jun 2016

Wei Benmei, Zhang Tianchi, Ou Xiaowen, Li Xinchun, Lou Xiaoding, Xia Fan

Abstract excerpt

Single nucleotide polymorphisms (SNPs) are the most abundant genetic polymorphisms and are responsible for many genetic diseases and cancers. In general, SNPs detection is performed by a single probe system (SPS), in which a single probe specifically hybridizes to one target. However, with the use of this method it is hard to improve the hybridization specificity and single mismatched discrimination factors (DF)....

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PMID: 27246659
DOI: 10.1021/acsami.6b03896

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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