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Article

Analysis of APBB2 gene polymorphisms in sporadic Alzheimer's disease.

Neuroscience letters - 12 Dec 2008

Golanska Ewa, Sieruta Monika, Gresner Sylwia M, Hulas-Bigoszewska Krystyna, Corder Elizabeth H, Styczynska Maria, Peplonska Beata, Barcikowska Maria, Liberski Pawel P

Abstract excerpt

The accumulation of beta-amyloid (Abeta) in the brain plays a central role in the pathogenesis of Alzheimer's disease (AD). The processing of Abeta precursor protein to Abeta is modulated by binding proteins including APBB2 [amyloid beta precursor protein-binding family B member 2, FE65-like, FE65L1]. We investigated two intronic SNPs within the APBB2 gene: rs13133980 and hCV1558625 (rs17443013), among Polish AD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adaptor Proteins, Signal Transducing
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Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 18852029
DOI: 10.1016/j.neulet.2008.10.003

Genes

APBB2
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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