Association between the ABCG2 C421A polymorphism and Alzheimer's disease.

doi:10.1016/j.neulet.2013.06.044

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Article

Association between the ABCG2 C421A polymorphism and Alzheimer's disease.

Neuroscience letters - 29 Aug 2013

Fehér Ágnes, Juhász Anna, László Anna, Pákáski Magdolna, Kálmán János, Janka Zoltán

Abstract excerpt

ATP binding cassette subfamily G member 2 (ABCG2) is involved in amyloid-β transport and was found to be significantly up-regulated in Alzheimer's disease (AD) brain. A functional polymorphism of the ABCG2 gene (C421A; rs2231142) was genotyped in a sample of 299 Hungarian late-onset AD patients and 259 elderly, non-demented controls to investigate for the first time its association with AD, either alone or in...

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PMID: 23827224
DOI: 10.1016/j.neulet.2013.06.044

Genes

ABCG2
APOE

Variants

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