Article
The cholesteryl ester transfer protein (CETP) gene and the risk of Alzheimer's disease.
Neurogenetics - 1 Aug 2007
Arias-Vásquez Alejandro, Isaacs Aaron, Aulchenko Yurii S, Hofman Albert, Oostra Ben A, Breteler Monique, van Duijn Cornelia M
Abstract excerpt
Like the apolipoprotein E (APOE) gene, the most common genetic determinant for Alzheimer's disease (AD), the cholesteryl ester transfer protein (CETP) is involved in lipid metabolism. We studied the I405V polymorphism of the CETP gene in relation to AD. We genotyped 544 AD cases and 5,404 controls from the Rotterdam study, using a TaqMan allelic discrimination assay. Odds ratios (ORs) for AD were estimated using...
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