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Article

An essential role of human Ada3 in p53 acetylation.

The Journal of biological chemistry - 23 Mar 2007

Nag Alo, Germaniuk-Kurowska Aleksandra, Dimri Manjari, Sassack Michael A, Gurumurthy Channabasavaiah Basavaraju, Gao Qingshen, Dimri Goberdhan, Band Hamid, Band Vimla

Abstract excerpt

The p53 tumor suppressor protein functions as a critical component of genotoxic stress response by regulating the expression of effector gene products that control the fate of a cell following DNA damage. Unstressed cells maintain p53 at low levels through regulated degradation, and p53 levels and activity are rapidly elevated upon genotoxic stress. Biochemical mechanisms that control the levels and activity of...

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Source

Identifiers

PMID: 17272277
DOI: 10.1074/jbc.M610443200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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