Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration

7 Apr 2016

Abstract excerpt

The integrity of the genome is maintained by a host of surveillance and repair mechanisms that are pivotal for cellular function. The tumour suppressor protein p53 is a major component of the DNA damage response pathway and plays a vital role in the maintenance of cell-cycle checkpoints. Here we show that a microRNA, miR-486, and its host gene ankyrin-1 (ANK1) are induced by p53 following DNA damage. Strikingly,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Erythrocyte Function and Pathophysiology
Share to MicroRNA in disease regulation
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27054339
DOI: 10.1038/cddis.2016.91

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migrationPMID 27054339Read ↗

Apoptosis and autophagy: Regulation of apoptosis by DNA damage signalling – roles of p53, p73 and HIPK2Semantic proximity Read ↗

Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11.Semantic proximity Read ↗

p53 regulates cytoskeleton remodeling to suppress tumor progression.Semantic proximity Read ↗

TRIM8 modulates p53 activity to dictate cell cycle arrestSemantic proximity Read ↗

p53-dependent DNA repair during the DNA damage response requires actin nucleation by JMYSemantic proximity Read ↗

microRNA-34a promotes DNA damage and mitotic catastrophe.Semantic proximity Read ↗

p53-dependent DNA repair during the DNA damage response requires actin nucleation by JMYSemantic proximity Read ↗

Reactivation of p53 by a Cytoskeletal Sensor to Control the Balance Between DNA Damage and Tumor DisseminationSemantic proximity Read ↗

A Pleiotropic RNA-Binding Protein Controls Distinct Cell Cycle Checkpoints to Drive Resistance of p53-Defective Tumors to Chemotherapy.Semantic proximity Read ↗

The nuclear structural protein NuMA is a negative regulator of 53BP1 in DNA double-strand break repairSemantic proximity Read ↗

Actin and microtubule cytoskeletons in the development and maintenance of cancer phenotypes. Preface.Semantic proximity Read ↗

The actin nucleation factors JMY and WHAMM enable a rapid p53-dependent pathway of apoptosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.