Article
The role of CYP2C9 gene polymorphisms on anticoagulant therapy after heart valve replacement.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre - 1 Jan 2008
Yildirim Hatice, Tamer Lülüfer, Sucu Nehir, Atik Uğur
Abstract excerpt
OBJECTIVE: The aim of the present study was to investigate the role of CYP2C9 gene polymorphisms after heart valve replacement in a group of patients on warfarin therapy. MATERIALS AND METHODS: The study population consisted of 74 patients with heart valve replacement. Peripheral blood was collected into evacuated tubes containing EDTA, and DNA was extracted from circulating leukocytes by using a high pure PCR...
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