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Article

Effect of CYP2C9 and VKORC1 genotypes on early-phase and steady-state warfarin dosing in Korean patients with mechanical heart valve replacement.

Pharmacogenetics and genomics - 1 Feb 2009

Kim Ho-Sook, Lee Sang Seop, Oh Minkyung, Jang Yin-Jin, Kim Eun-Young, Han Ii Yong, Cho Kwang-Hyun, Shin Jae-Gook

Abstract excerpt

OBJECTIVES: The effect of CYP2C9 and vitamin K epoxide reductase complex subunit 1 (VKORC1) genotypes was evaluated for the early-phase and steady-state warfarin dosing in Korean patients with mechanical heart valve replacement. METHODS: The genotypes of CYP2C9 variants including CYP2C9*3, CYP2C9*13, and CYP2C9*14, and VKORC1 1173C>T were assessed for the association with warfarin dosing in 265 patients whose...

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Source

Identifiers

PMID: 19077919
DOI: 10.1097/FPC.0b013e32831a9ae3

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effect of CYP2C9 and VKORC1 genotypes on early-phase and steady-state warfarin dosing in Korean patients with mechanical heart valve replacement.PMID 19077919Read ↗

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