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Article

Characterization of aripiprazole partial agonist activity at human dopamine D3 receptors.

European journal of pharmacology - 12 Nov 2008

Tadori Yoshihiro, Forbes Robert A, McQuade Robert D, Kikuchi Tetsuro

Abstract excerpt

Aripiprazole is the first dopamine D2/D3 receptor partial agonist approved for use in the treatment of psychiatric disorders, including schizophrenia, bipolar disorder, and unipolar depression in the US. To explore the functional activity of aripiprazole at dopamine D3 receptors, we established Chinese hamster ovary (CHO) cell lines stably expressing high and low densities of Ser-9 and Gly-9 variants of human...

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Identifiers

PMID: 18831971
DOI: 10.1016/j.ejphar.2008.09.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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