Article
Evidence for Protein-Protein Interaction between Dopamine Receptors and the G Protein-Coupled Receptor 143.
International journal of molecular sciences - 3 Aug 2021
Bueschbell Beatriz, Manga Prashiela, Penner Erika, Schiedel Anke C
Abstract excerpt
Protein-protein interactions between G protein-coupled receptors (GPCRs) can augment their functionality and increase the repertoire of signaling pathways they regulate. New therapeutics designed to modulate such interactions may allow for targeting of a specific GPCR activity, thus reducing potential for side effects. Dopamine receptor (DR) heteromers are promising candidates for targeted therapy of neurological...
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