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Design, Synthesis, and Evaluation of Functionalized 5-(4-arylpiperazin-1-yl)-N-Quinolinyl-pentanamides as Selective Dopamine D3 Receptor Ligands

2021-11-30

Abstract excerpt

<title>Abstract</title> <p>Dopamine (<bold>1</bold>) plays a key role in normal physiological pathways in both the central nervous system and the periphery. The physiological impact of this neurotransmitter is mediated through its interaction with family of G-protein-coupled receptors (GPCRs). These receptors are designated as D<sub>1</sub>, D<sub>2</sub>, D<sub>3</sub>, D<sub>4</sub>, and D<sub>5</sub> and divid...

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Literature Corpus work
d1e5bec4-0acc-5f9e-a08a-610435b3b5b5
DOI
10.21203/rs.3.rs-1097103/v1
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Design, Synthesis, and Evaluation of Functionalized 5-(4-arylpiperazin-1-yl)-N-Quinolinyl-pentanamides as Selective Dopamine D3 Receptor LigandsDOI 10.21203/rs.3.rs-1097103/v1
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