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Article

Identification of amino acid determinants of dopamine 2 receptor synthetic agonist function.

The Journal of pharmacology and experimental therapeutics - 1 Apr 2007

Al-Fulaij Munya A, Ren Yong, Beinborn Martin, Kopin Alan S

Abstract excerpt

The human dopamine 2 receptor (hD2R) modulates locomotor activity, hormone secretion, and neuropsychiatric function. Current knowledge of the hD2R structure is in large part derived from mutagenesis studies and molecular pharmacologic analysis together with homology modeling using bovine rhodopsin as a template. In this study, we utilized comparison of the Drosophila D2-like receptor (DD2R) with the hD2R as a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17204745
DOI: 10.1124/jpet.106.116384

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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