Article
Evaluation of denaturing high-performance liquid chromatography as a rapid detection method for identification of epidermal growth factor receptor mutations in nonsmall-cell lung cancer.
Cancer - 15 Dec 2006
Cohen Victor, Agulnik Jason S, Jarry Jonathan, Batist Gerald, Small David, Kreisman Harvey, Tejada Neely Adriana, Miller Wilson H, Chong George
Abstract excerpt
BACKGROUND: Somatic mutations of the epidermal growth factor receptor (EGFR) gene in nonsmall-cell lung cancer (NSCLC) may predict responsiveness to tyrosine kinase inhibitors. These mutations are commonly identified using DNA sequencing methods. Although considered the gold standard, this approa...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.