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Article

Increase EGFR Mutations Detection Rate in Lung Adenocarcinoma by Real-Time PCR Screening Followed by Direct Sequencing.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Jan 2000

Er Tze-Kiong, Lin Chin-Wen, Liu Ta-Chih, Chen Chih-Chieh, Wang Li-Hsuan, Hsieh Li-Ling, Tsai Wen-Chan

Abstract excerpt

BACKGROUND: Recently, a number of small-molecule tyrosine kinase inhibitors (TKIs) have been developed to target the ATP-binding cleft of the epidermal growth factor receptor (EGFR). The presence of EGFR mutations in non-small cell lung cancer (NSCLC) correlates with the responsiveness to TKIs. Therefore, the identification of EGFR mutations before the administration of TKIs of NSCLC has become important. The aim...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25961746
DOI: 10.1097/PDM.0000000000000037

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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