Article
Epidermal growth factor receptor mutations in cells from non-small cell lung cancer malignant pleural effusions.
Chang Gung medical journal - 1 Jan 2000
Hung Ming-Szu, Lin Chin-Kuo, Leu Shaw-Wei, Wu Mei-Yi, Tsai Ying-Huang, Yang Cheng-Ta
Abstract excerpt
BACKGROUND: The prevalence of epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) patients is about 40-50% in Taiwan, and there are significant correlations between EGFR mutations and clinical responses after gefitinib treatment. For most patients with advanced disease, surgical intervention for tissue sampling is not feasible. We therefore conducted this study to survey EGFR...
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