Article
[Features of mutated changes of genomic RNA of cold-adapted and hr-variants of influenza group A virus, detected by RNA:RNA hybridization].
Molekuliarnaia genetika, mikrobiologiia i virusologiia - 1 Nov 1990
Klimov A I, Iotov V V
Abstract excerpt
The presence of mutations in the majority of the genes of cold-adapted strains A/Leningrad/134/17/57 (H2N2), A/Leningrad/134/47/57 (H2N2) and A/PR/8/59/1 (H1N1) of influenza A virus has been demonstrated by the RNA-RNA hybridization with the subsequent electrophoresis of double-stranded RNA in 7.5% polyacrylamide gel. The strains were cultivated 17, 47 and 59 passages in the chicken embryos at 25 degrees C. In...
Topics
- Antigens, Viral
- Cold Temperature
- Electrophoresis, Polyacrylamide Gel
- Epitopes
- Genes, Viral
- Influenza A virus
- Mutation
- Nucleic Acid Hybridization
- RNA, Double-Stranded
- RNA, Messenger
- RNA, Viral