Article
[Immunogenicity of attenuated reassortants of influenza A virus /Leningrad/134/47/57 (H2N2) for mice, depending on their genome].
Voprosy virusologii - 1 Jan 2000
Egorov A Iu, Garmashova L M, Nevedomskaia G N, Bogomolova L I, Khaĭder A M, Aleksandrova G I
Abstract excerpt
Reassortants of cold-adapted strain A/Leningrad/134/47/57 (H2N2) and virulent strain A/PR/8/34 (H1N1), modeling genomic composition of vaccinal strains, were tried in mouse experiments. Reassortants' genomes included the major part (5, 6, or 7) from cold-adapted strain and 1 to 3 genes of virulen...
Topics
- Animals
- Cold Temperature
- Genome, Viral
- Influenza A Virus, H2N2 Subtype
- Influenza A virus
- Influenza Vaccines
- Lung
- Mice
- Mice, Inbred CBA
- Phenotype
- Vaccines, Attenuated
- Virus Replication
