Article
Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort.
Gut - 1 Mar 2009
Weersma R K, Stokkers P C F, van Bodegraven A A, van Hogezand R A, Verspaget H W, de Jong D J, van der Woude C J, Oldenburg B, Linskens R K, Festen E A M, van der Steege G, Hommes D W, Crusius J B A, Wijmenga C, Nolte I M, Dijkstra G
Abstract excerpt
BACKGROUND: Crohn's disease and ulcerative colitis have a complex genetic background. We assessed the risk for both the development and severity of the disease by combining information from genetic variants associated with inflammatory bowel disease (IBD). METHODS: We studied 2804 patients (1684 with Crohn's disease and 1120 with ulcerative colitis) and 1350 controls from seven university hospitals. Details of...
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