Article
New IBD genetics: common pathways with other diseases.
Gut - 1 Dec 2011
Lees C W, Barrett J C, Parkes M, Satsangi J
Abstract excerpt
Complex disease genetics has been revolutionised in recent years by the advent of genome-wide association (GWA) studies. The chronic inflammatory bowel diseases (IBDs), Crohn's disease and ulcerative colitis have seen notable successes culminating in the discovery of 99 published susceptibility loci/genes (71 Crohn's disease; 47 ulcerative colitis) to date. Approximately one-third of loci described confer...
Topics
- Arthritis, Rheumatoid
- Asthma
- Colitis, Ulcerative
- Crohn Disease
- Dermatitis, Atopic
- Diabetes Mellitus, Type 1
- Genetic Loci
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Inflammatory Bowel Diseases
- Lupus Erythematosus, Systemic
- Mycobacterium Infections
- Psoriasis
- Spondylitis, Ankylosing