Article
Genetics of inflammatory bowel disease from multifactorial to monogenic forms.
World journal of gastroenterology - 21 Nov 2015
Bianco Anna Monica, Girardelli Martina, Tommasini Alberto
Abstract excerpt
Inflammatory bowel disease (IBD) is a group of chronic multifactorial disorders. According to a recent study, the number of IBD association loci is increased to 201, of which 37 and 27 loci contribute specifically to the development of Crohn's disease and ulcerative colitis respectively. Some IBD associated genes are involved in innate immunity, in the autophagy and in the inflammatory response such as NOD2,...
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