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Article

Microbead device for isolating biotinylated oligonucleotides for use in mass spectrometric analysis.

Analytical biochemistry - 1 Jan 2009

Misra Ashish, Kim Sobin

Abstract excerpt

We describe a prototypical device for isolating biotinylated oligonucleotides for use in mass spectrometric analysis. It consists of monomeric avidin-coated microbeads trapped in a pipette tip and has been used for genotyping single nucleotide polymorphisms (SNPs) with the previously developed solid phase capture-single base extension (SPC-SBE) method. The device reduces processing time for genotyping by SPC-SBE...

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Identifiers

PMID: 18823931
DOI: 10.1016/j.ab.2008.09.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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