Article

Protein-Formatted Biomarker Enrichment Tag for the Detection of Carcinoembryonic Antigen

2025-01-19

Abstract excerpt

The streptavidin-biotin interaction has long been a cornerstone of immunoassays, valued for its exceptionally high affinity and specificity, and has been widely used in routine diagnostic assays for decades. However, elevated biotin levels in plasma, often resulting from oral supplements, can interfere with streptavidin-biotin binding, compromising signal detection in these assays. To address this limitation, we p...

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Literature Corpus work: e502184b-02d0-5076-a84c-c78a34d2bf11
DOI: 10.1101/2025.01.15.633204

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