Article
Microfluidic bead trap as a visual bar for quantitative detection of oligonucleotides.
Lab on a chip - 26 Sept 2017
Zhao Zichen, Bao Yuanye, Chu Lok Ting, Ho John Kin Lim, Chieng Ching-Chang, Chen Ting-Hsuan
Abstract excerpt
We demonstrate a microfluidic bead trap capable of forming a dipstick-type bar visible to the naked eye for simple and quantitative detection of oligonucleotides. We use magnetic microparticles (MMPs) and polystyrene microparticles (PMPs) that are connected and form MMPs-targets-PMPs when target oligonucleotides are present, leaving free PMPs with a number inversely proportional to the amount of targets. Using a...
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