Article
A molecular beacon microarray based on a quantum dot label for detecting single nucleotide polymorphisms.
Biosensors & bioelectronics - 15 Mar 2016
Guo Qingsheng, Bai Zhixiong, Liu Yuqian, Sun Qingjiang
Abstract excerpt
In this work, we report the application of streptavidin-coated quantum dot (strAV-QD) in molecular beacon (MB) microarray assays by using the strAV-QD to label the immobilized MB, avoiding target labeling and meanwhile obviating the use of amplification. The MBs are stem-loop structured oligodeoxynucleotides, modified with a thiol and a biotin at two terminals of the stem. With the strAV-QD labeling an "opened"...
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