Article
A genome-wide association study for late-onset Alzheimer's disease using DNA pooling
29 Sept 2008
Abstract excerpt
BACKGROUND: Late-onset Alzheimer's disease (LOAD) is an age related neurodegenerative disease with a high prevalence that places major demands on healthcare resources in societies with increasingly aged populations. The only extensively replicable genetic risk factor for LOAD is the apolipoprotein E gene. In order to identify additional genetic risk loci we have conducted a genome-wide association (GWA) study in...
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