Article
The National Institute on Aging Late-Onset Alzheimer's Disease Family Based Study: A resource for genetic discovery.
Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Oct 2022
Reyes-Dumeyer Dolly, Faber Kelley, Vardarajan Badri, Goate Alison, Renton Alan, Chao Michael, Boeve Brad, Cruchaga Carlos, Pericak-Vance Margaret, Haines Jonathan L, Rosenberg Roger, Tsuang Debby, Sweet Robert A, Bennett David A, Wilson Robert S, Foroud Tatiana, Mayeux Richard
Abstract excerpt
INTRODUCTION: The National Institute on Aging Late-Onset Alzheimer's Disease Family Based Study (NIA-LOAD FBS) was established to study the genetic etiology of Alzheimer's disease (AD). METHODS: Recruitment focused on families with two living affected siblings and a third first-degree relative similar in age with or without dementia. Uniform assessments were completed, DNA was obtained, as was neuropathology,...
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