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Article

A note on plating efficiency in fluctuation experiments.

Mathematical biosciences - 1 Dec 2008

Zheng Qi

Abstract excerpt

In estimating mutation rates using the Luria-Delbrück experimental protocol, it is often assumed that all mutant cells survive the plating procedure to form visible mutant colonies. This assumption of perfect plating efficiency may not hold in certain circumstances, but none of the existing estimation methods that adjust for plating efficiency is strictly based on the likelihood principle. To ameliorate this...

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PMID: 18822300
DOI: 10.1016/j.mbs.2008.09.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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